Because PB Serum works by reducing localized fat and remodeling tissue, the wrong patient selection can sometimes lead to an overly hollow or aged appearance.
PB Serum may not be suitable for patients with:
Naturally slim or narrow faces
Significant facial volume loss
Facial sagging caused by ligament laxity rather than excess fat
Deep nasolabial folds due to midface descent
Hollow cheeks or temples
Advanced skin laxity
Significant weight loss or GLP-1 related facial volume loss
Patients seeking lifting rather than contouring
One of the most common misconceptions in aesthetic medicine is assuming that every lower face concern is caused by excess fat.
For example, if your nasolabial folds are caused by:
Cheek deflation
Loss of collagen
Facial sagging
Structural volume loss
Reducing fat in these patients may actually make the folds appear deeper and the face look more sunken.
In these cases, treatments that stimulate collagen or restore structural support may be more appropriate than fat reduction.
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"I like PB Serum, but I do not recommend it to everyone.
If you are slim and your nasolabial fold is caused by sagging rather than excess fat, reducing facial fat may leave you with a more hollow appearance and you may regret the result later.
Diagnosis matters more than the product itself."
The ideal PB Serum patient typically has:
Localized fat deposits
Mild lower face heaviness
Double chin fullness
Early jowling caused by excess fat rather than skin laxity
Good skin elasticity
At Sheen Clinic, treatment recommendations are based on facial anatomy, aging patterns and treatment goals rather than trends or one-size-fits-all solutions.
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