Tritace 10 /mg is indicated for the following adult patients:
Hypertension (high blood pressure), alone or in combination with other antihypertensives
Congestive heart failure (symptomatic), as adjunct therapy
Secondary prevention after myocardial infarction in patients with signs of heart failure (>48 hours post event)
Reduction of cardiovascular risk or delay of progression in patients with established atherothrombotic disease or diabetes plus one or more risk factors
Prevention or progression of renal disease, including diabetic or non diabetic nephropathy with proteinuria
The daily dose should be individualized based on patient condition, especially blood pressure, renal function, and comorbidities
Typical titration: start from 1.25–2.5 mg daily and gradually increase to a maintenance dose of 5–10 /mg/day (once or twice daily) depending on clinical response
In hypertensive patients on diuretics, start at 1.25 mg daily
Renal impairment dosing varies: e.g., if CrCl 30–60 /mL/min, max dose 5 mg/day; CrCl < /30 /mL/min, start 1.25 mg/day with max 5 mg/day
Swallow tablet whole with water
Do not chew, crush or break the tablet
Can be taken with or without food (food does not affect absorption)
Take at the same time each day to maintain steady effect
Take the missed dose as soon as possible unless it is nearly time for the next dose.
Do not double up doses
Regular assessment of blood pressure, renal function, and serum electrolytes (especially potassium) is recommended during initiation and dose changes
Malaysia
