详情
Manufacturer
Merck Sharp & Dohme
Registraction Number
MAL20070334
Content
- Each tablet contains 50 mg of sitagliptin phosphate monohydrate, the active ingredient that works as a dipeptidyl peptidase-4 (DPP-4) inhibitor to help improve blood sugar control in type 2 diabetes.
Indication
- Januvia is used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus.
- It can be used alone or in combination with other antidiabetic medications such as metformin, sulfonylureas, or insulin when these alone do not provide adequate control.
Instructions for Use
- Recommended dose: 50 mg once daily.
- It can be taken with or without food.
- Dosage adjustment is required in patients with renal impairment:
- For moderate renal impairment (eGFR ≥30 to <45 mL/min/1.73 m²): 50 mg once daily.
- For severe renal impairment (eGFR <30 mL/min/1.73 m²) or end-stage renal disease requiring dialysis: 25 mg once daily.
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