Vytorin is a combination of:
Ezetimibe (10 mg) – reduces intestinal absorption of cholesterol.
Simvastatin (40 mg) – reduces cholesterol production in the liver.
Primary hypercholesterolemia (familial and non-familial)
Mixed hyperlipidemia
Homozygous familial hypercholesterolemia (HoFH) – used with additional lipid-lowering treatments (e.g., LDL apheresis)
Coronary heart disease (CHD)
Acute coronary syndrome (ACS)
Reduces risk of:
Heart attack (MI)
Stroke
Revascularization procedures (e.g., angioplasty)
Cardiovascular-related death
Always follow your doctor’s specific instructions.
Usual Dose: 1 tablet once daily
Preferred timing: In the evening
With or without food
The 10/40 mg dose is often:
Initiated in patients needing moderate to major cholesterol reduction
Continued if lower doses are not sufficient
Note: The maximum dose is 10/80 mg daily. Use of 10/80 /mg is restricted due to a higher risk of muscle injury unless the patient has been taking it for over 12 months without issues.
Malaysia