The Advanced NICC Test is a non-invasive prenatal test (NIPT) that analyses fetal cell-free DNA (cfDNA) from a simple maternal blood sample. It provides extended chromosomal screening for the baby and is suitable from 10 weeks of pregnancy onwards.
This test is designed for expectant parents who want more detailed genetic information beyond basic NIPT screening.
Screens for common and selected additional chromosomal trisomies, including:
• Trisomy 21 (Down Syndrome)
• Trisomy 18 (Edwards Syndrome)
• Trisomy 13 (Patau Syndrome)
• Trisomy 9, 16, and 22
(Sex Chromosome Abnormalities)
Screens for conditions involving sex chromosomes, including:
• Turner Syndrome (XO)
• Triple X Syndrome (XXX)
• Klinefelter Syndrome (XXY)
• Jacob’s Syndrome (XYY)
• Plus 22 other chromosomal aneuploidies
(Microdeletion / Microduplication Analysis)
The Advanced NICC NIPT includes screening for 92 clinically significant microdeletion and microduplication syndromes, which involve small missing or duplicated segments of chromosomes.
These conditions may not always be detected through routine ultrasound alone.
Fetal gender can be identified from 10 weeks onwards,
subject to medical advice and local regulations.
A dedicated consultation with our Klinik Caring doctors to:
• Explain your NIPT results clearly
• Discuss their clinical significance
• Advise on appropriate next steps if needed
The Advanced NICC Test (NIPT) is ideal for parents who want broader chromosomal screening without maternal genetic carrier testing.
It is commonly chosen by parents who:
• Want more than basic NIPT screening
• Have ultrasound findings that require further assessment
• Prefer early, detailed genetic insight
• Want reassurance through extended chromosomal analysis
This non-invasive NIPT blood test is safe for both mother and baby and does not carry a miscarriage risk.
At Klinik Caring, we prioritise clear explanations, careful counselling, and personalised care throughout your pregnancy journey.
The Advanced NICC Test is an advanced non-invasive prenatal test (NIPT) that screens for common trisomies, additional chromosomal aneuploidies, and a wide range of microdeletion and microduplication syndromes in the baby.
The test can be performed from 10 weeks of pregnancy onwards.
Yes. It is a non-invasive blood test taken from the mother and poses no risk to the baby.
The key difference is maternal genetic carrier screening.
• Advanced NICC (NIPT)
Focuses on fetal chromosomal abnormalities and microdeletion/microduplication syndromes.
• Advanced Plus NICC (NIPT)
Includes almost everything in Advanced NICC plus maternal screening for 18 single-gene recessive disorders, such as thalassemia and G6PD deficiency.
If your main concern is fetal chromosomal health, Advanced NICC (NIPT) is a comprehensive option.
If you would also like to assess maternal genetic carrier risks, Advanced Plus NICC (NIPT) may be more suitable.
No. NIPT is a screening tool and does not replace routine ultrasound scans or standard antenatal care.
The Advanced NICC Test (NIPT) is available at Klinik Caring, conveniently serving patients from Skudai, Impian Emas, and the wider Johor Bahru area.
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