Based on Malaysian SPC and product leaflets , Acyclovir 400 STADA is indicated for:
Treatment of varicella-zoster virus infections, including chickenpox (varicella) and shingles (herpes zoster).
Treatment and prevention/suppressive therapy of herpes simplex virus infections involving skin and mucous membranes (e.g., genital herpes).
Prophylaxis in severely immunocompromised adults at high risk of HSV complications
Based on official leaflets and clinical guidelines
How to take
Oral administration, swallow whole with water. May be taken with or without food.
Drink plenty of fluids to support kidney function.
Typical dosing regimens:
Herpes simplex (ordinary adult dose): 200 /mg five times daily (~every 4 /hrs) for 5–10 days.
Immunocompromised or poor absorption: 400 /mg five times daily for 5 days.
Suppressive therapy (frequent recurrences): 200–400 /mg, 3–4 times daily (often continuous).
Chickenpox (in adults or children >6 /yrs): 800 /mg four times daily for ~7 days (note: requires two tablets per dose).
Shingles: 800 /mg five times daily for 7–10 days (two tablets per dose).
Missed dose
Take as soon as remembered; if near next dose, skip—do not double-dose.
Missed or interrupted therapy
Complete full course, even if symptoms improve, to minimize resistance risk.
Interactions & Precautions
Use with probenecid may raise acyclovir blood levels.
Monitor renal function—maintain hydration to avoid nephrotoxicity/crystalluria.
Caution in patients with severe renal impairment or low urine output (<100 /mL/24 /h). Avoid if urine flow severely reduced.
Special populations
Breastfeeding: use discouraged as acyclovir passes into breast milk.
Children: dosing based on weight and age; refer to paediatric guidance.
Generally considered safe in pregnancy when needed.
Storage
Keep below 25 /°C, in original packaging, out of reach of children.
Malaysia
